Glycocenosls Associated with Glu - Cose

S OF SPECIAL INTEREST CELLULAR ANI-lwmIEs IN KiDNEY HoMo rst NSPLANTATION. A. Gocaerts. Fronl the Pasteur Institute, Brussels, Belgiunl. J. Inlnlunoi. 85:516522, 1960. The action of ser t and lynlphocytes from kidney homografted dogs on tissue cultures from the second kidney of the donor was studied. Sera alone taken from animals after rejecting the graft showed no cytotoxic action on the cultures. Living lymphocytes from the illlmtlnized recipients, however, regularly produced cytotoxic lesions in renal cultures from tile corresponding donors but not in cultures froni other dogs. The cytotoxic effect seemed to depend oti the coincident presence of imnlune serum from the recipients. Interestingly, living lymphtocytes fronl tile recipients were not found to be obvu)usiy toxic for Wilite cell suspensions oi)taine(l froni tue lk’ritoileal fluid of the donors-i’. E. B. THE DisposAl. OF InITIATED h)1.IC AcID INJECTED INTRAVENOUSLY IN MAN. D. G. Johns, S. Sperti and A. S. V. Btirgen. From the Montreal Ceneral Hospital. Canad. \I. A. j. 84:77, 1961. Tritiated ptcroyigiutaniic acid as found to be cleared fronl 1)iiSIlhl of nornial suh ccts as would i)e expected if it were not tritiated. As indicated by the study of Anderson, Belcher, Chanarin, and Mollin ( Brit. J. Haemat. 6:439, 1960), and the present authors, tritiated folic acid may prove especially useful in studying the absorption of folic acid-V. H. HUMAN ALBUMIN IN EXCHANGE TRANSFUSION. W. H. Kitchen, V. I. Krieger and M. A. Smith. From the Royal Wonlen’s Hospital, Melbourne, Australia. J. Pediat. 57:876-883, 1960. Since hiiirubin in tile plasma circulates bound to albumin, and unboun(i hilirubin is free to escape into the tissues. an attempt was made to increase the amount of circulating bilirubin, prior to exchange transfusion. Twelve-and-a-half Gm. of salt-poor albumin were l(Inhinistered intravenously to erythroblastotic infants before, and again in the niiddk’ of, an exchange transfusion. The total amount of bilirubin removed from the body by tile exchange traiisfusioii was then measured. It was found tllat significantly greater amounts of bilirubin were removed from the albumin-treated infants tilan fronl a group of control infants. It is suggested that the administration of albumin before anti thiring the first exchange transfusion, by increasing the alilolint of hilirubin renloved, will result in a decreased iieed for multiple exchange transfusions-I. B. S. For personal use only. on October 21, 2017. by guest www.bloodjournal.org From